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Haemostasis and thrombosis: an overview

H. Rasche
DOI: http://dx.doi.org/10.1016/S1520-765X(01)90034-3 Q3-Q7 First published online: 1 December 2001


The present review provides a review of haemostasis and thrombosis. It describes the basic mechanisms of the blood's coagulable states, as well as their associated bleeding and thromboembolic disorders. Endothelial cells present a nonthrombogenic surface. In contrast, after contact of blood with a synthetic surface (e.g. mechanical heart valves) local thrombus formation and embolism can occur. Anticoagulant therapy is required to prevent these complications in patients with artificial implants.

  • Haemostasis
  • thrombosis
  • bleeding disorders
  • thrombophilia