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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Early invasive strategy in the diabetic patient with non-ST-segment elevation acute coronary syndromes

Marco Roffi*

Division of Cardiology, University Hospital, Zurich, Switzerland

* Corresponding author. Tel: +41 1 255 8573; fax: +41 1 255 4401. E-mail address: marco.roffi{at}usz.ch

Diabetic patients with non-ST-segment elevation acute coronary syndromes are at high risk for subsequent cardiovascular events. At the same time, however, they derive greater benefit than non-diabetic counterparts from an aggressive acute-phase management based on platelet glycoprotein IIb/IIIa receptor antagonists and an early invasive strategy. Despite the benefit, these treatment modalities remain underutilized among patients with diabetes mellitus. The widespread use of drug-eluting stents will further improve outcomes in patients with diabetes undergoing early percutaneous revascularization. In this patient population, the sirolimus-eluting stent appears to be superior to the paclitaxel-coated one.

Key Words: Diabetes mellitus • Acute coronary syndromes • Early invasive strategy • Glycoprotein IIb/IIIa receptor inhibitors • Drug-eluting stents


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