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Foreword

J.C. LaRosa*

State University of New York, Downstate Medical Center, NY, USA

T.R. Pedersen

Aker University Hospital, Oslo, Norway

* Correspondence: J.C. LaRosa, State University of New York, Downstate Medical Center, 450 Clarkson Avenue, Box 1, Brooklyn, NY 11203, USA. Fax: +1-718-270-4732.
lrosbruck@netmail.hscbklyn.edu

t.r.Pedersen@ioks.uio.no

The first 150 words of the full text of this article appear below.

Human life expectancy at birth has steadily increased from the beginning of recorded history to the present time. In ancient Rome, it was approximately 20 years, and it took 4000 years, to the mid-19th century, to double. From the mid-19th century to the present, it has almost doubled again. The prevention of atherosclerosis, however, has not played much of a role in that life extension. On the contrary, atherosclerosis, on a worldwide basis, is becoming more, rather than less, of a problem.

The first written description of atherosclerosis was by Joseph Conrad Bruner who, in 1695, described `hardening' of the aorta and major blood vessels in an autopsy. In 1768, William Heberden described angina pectoris, based on 20 observed cases, which increased to 100 cases by 1782. In 1852, Carl Von Rokitansky described the pathology of atheroma and originated the `thrombogenic' or `encrustation' theory of atherosclerosis, and in 1856 Rudolf . . . [Full Text of this Article]

The factors for atherosclerosis increase

Statins for cholesterol lowering


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