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The European Society Cardiology

Coronary heart disease risk in Japan – an East/West divide?

T Kita*

Kyoto University, Kyoto, Japan

* Toru Kita, Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, 54 Kawara-cho Shogoin Sakyo-ku, Kyoto 606-8507, Japan. Tel.: +81-75-751-3158; fax: +81-75-752-0856
tkita{at}kuhp.kyoto-u.ac.jp

Abstract

Lower rates of coronary heart disease (CHD) and other cardiovascular disease in the Japanese population compared with the US and other Western populations suggest the possibility of genetic differences that confer some protection from such disease in Japanese people. However, lifestyle changes in Japan in recent decades have been accompanied by the increasing prevalence of hypercholesterolaemia and diabetes, and recent data indicate an increase in prevalence of ischaemic heart disease. Studies in Japan have indicated a strong relationship between hypercholesterolaemia and CHD. Close attention must be devoted to what appears to be a growing risk for cardiovascular disease in the Japanese population.

Key Words: Coronary heart disease • Japanese • Hypercholesterolaemia • Cardiovascular risk • Western • Diabetes


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