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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

The balance between bleeding and ischaemic complications in percutnaeous coronary intervention practice

David Antoniucci*

Division of Cardiology, Careggi Hospital, Florence, Italy

* Corresponding author. Viale Morgagayi 85, 50134. Tel: +39 055 7947966. E-mail address: david.antoniucci@virglio.it

Key Words: Bleeding • Percutaneous coronary intervention

The first 150 words of the full text of this article appear below.

Strong antithrombotic treatments may decrease the risk of recurrent ischaemic events in patients with acute coronary syndromes (ACS) and, as adjunctive therapy to percutaneous coronary intervention (PCI), they have shown a strong clinical benefit. However, a significant decrease in the risk of ischaemic complications is invariably associated with an increased risk of bleeding and there is growing evidence that bleeding in patients with ACS has a strong impact on survival.1 It is not easy to ascertain the true impact of bleeding on clinical outcome in patients undergoing PCI due to the need of large sample of patients to avoid the confounding effect of the worse baseline risk profile of patients who suffer bleeding, the need for an appropriate definition of the severity of bleeding complications, the confounding effect of many variables that are linked to bleeding and that are unexplored in most studies, such as the dose and duration of . . . [Full Text of this Article]


   The definition of major bleeding
 

   Bleeding as a predictor of poor outcome
 

   The balance between bleeding and ischaemic complications in percutaneous coronary intervention practice
 

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