Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org
Recent advances in the management of atrial fibrillation
David Geffen School of Medicine at UCLA, and VA Greater Los Angeles Health Care System, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA
* Corresponding author. Tel: +1 310 268 3436; fax: +1 310 473 0724. E-mail address: bramah.singh@va.gov or bsingh@ucla.edu
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Atrial fibrillation (AF) is the most common cardiac arrhythmia in clinical practice, with over 3 million cases in the USA and 4.5 million in Europe. Its incidence is rising rapidly, and the number of individuals with AF is expected to triple or even quadruple between now and 2050. Most patients with AF are over 65 years of age and present many co-morbidities, in particular, hypertension (37%), heart failure (23%), coronary artery disease (18%), and diabetes (15%). The majority of patients with AF are elderly and 83% are aged over 65 years. This subset of patients is likely to continue to increase in number. AF is a major source of morbidity and mortality, being associated with reduced left ventricular function, exercise tolerance and quality of life, as well
| The CREATE Scientific Committee 2007 |
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