Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org
EUROPEAN HEART JOURNAL SUPPLEMENTS
Key lessons from morbidity/mortality trials: evidence for benefits of the perindopril/amlodipine combination ESC MUNICH 2008
1 Department of Cardiology, Università degli Studi di Ferrara, Italy
2 Cardiovascular Research Center IRCCS, Salvatore Maugeri Foundation, Gussago, Brescia, Italy
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In the last 50 years, mean life span has increased by almost 8 years. Cardiology has played an important role in this achievement. It has been estimated that the contribution of cardiology to the extension of life accounts for almost 6 years!
This depends in part, of course, on the fact that cardiovascular disease itself contributes to more than 50% of total mortality of population, but also largely on the success of interventional cardiology and cardiovascular therapy.
The contribution of revascularization by any means, but particularly by primary angioplasty, has changed the natural history of acute myocardial infarction (MI) to the extent that, today, the need for intensive care units to treat acute MI is often questioned. Equally, there have been huge advances in heart surgery for revascularization of complex coronary, valvular, and congenital diseases, and