Skip Navigation

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Grundy, S. M.
PubMed
Right arrow Articles by Grundy, S. M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The European Society of Cardiology 2008. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

A changing paradigm for prevention of cardiovascular disease: emergence of the metabolic syndrome as a multiplex risk factor

Scott M. Grundy*

Center for Human Nutrition, Departments of Clinical Nutrition and Internal Medicine, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-9052, USA

* Corresponding author. Tel: +1 214 648 2890; fax: +1 214 648 4837.E-mail address: scott.grundy{at}utsouthwestern.edu

The traditional major risk factors for cardiovascular disease (CVD) are cigarette smoking, hypertension, elevated serum cholesterol, and hyperglycaemia (diabetes). The majority of patients with CVD have multiple risk factors. In recent years a common pattern of multiple risk factors has emerged. This is the metabolic syndrome, which is driven largely by obesity. The metabolic syndrome is particularly important because it is a multiplex risk factor for both CVD and Type 2 diabetes. Although obesity is the primary cause of the metabolic syndrome, there are other endogenous and exogenous factors.

Key Words: Atherogenic dyslipidaemia • Atherosclerosis • Cardiovascular disease • Metabolic syndrome • Type 2 diabetes


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.