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Haemostasis and thrombosis: an overview

H. Rasche*

Department of Hematology, Center of Internal Medicine, Zentralkrankenhaus, Bremen, Germany

* Correspondence: Prof. Dr H. Rasche, Department of Hematology, Center of Internal Medicine, Zentralkrankenhaus St-Jürgen-Str. 1, D-28205 Bremen, Germany.

Abstract

The present review provides a review of haemostasis and thrombosis. It describes the basic mechanisms of the blood's coagulable states, as well as their associated bleeding and thromboembolic disorders. Endothelial cells present a nonthrombogenic surface. In contrast, after contact of blood with a synthetic surface (e.g. mechanical heart valves) local thrombus formation and embolism can occur. Anticoagulant therapy is required to prevent these complications in patients with artificial implants.

Key Words: Haemostasis • thrombosis • bleeding disorders • thrombophilia

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