Skip Navigation

This Article
Right arrow Abstract Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Disclaimer
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Shaw, L.J.
Right arrow Articles by Miller, D.D.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Shaw, L.J.
Right arrow Articles by Miller, D.D.
Social Bookmarking
 Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?


Cost-effectiveness of myocardial perfusion imaging in the evaluation of patients with known or suspected coronary artery disease

L.J. Shaw*, D.S. Berman and D.D. Miller

Rollins School of Public Health, Emory University, Atlanta, Georgia, U.S.A.

* Correspondence: Leslee J. Shaw, PhD, Room 638, 1518 Clifton Rd NE, Department of Health Policy and Management, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, U.S.A.

Abstract

Substantial evidence supports the clinical application of myocardial perfusion imaging (MPI) in patients with suspected or chronic coronary artery disease (CAD). Current recommendations encourage the use of MPI for prognostication and as a ‘gatekeeper’ to cardiac catheterization. Moreover, recent economic evidence indicates that MPI, as a result of improved diagnosis and risk estimation, provides substantial cost savings when compared with other competitive modalities for suspected and known CAD. Thus, on the basis of both clinical and cost considerations, MPI is increasingly viewed as a cost-effective, non-invasive test that can be used to optimize management in patients with CAD.

Key Words: Cost-effectiveness • myocardial perfusion imaging • economic evaluation

References

  1. Fuster V. Epidemic of cardiovascular disease and stroke. Circulation. 1999;99:1132–1137[Free Full Text]
  2. Levit KR, Lazensby HC, Braden BR. National health expenditures. Health Affairs. 1996;17:35–51
  3. Burner ST, Waldo DR, McKusick DR. National health care expenditures. Health Care Financing Review. 1996;14:1–30
  4. Available athttp://www.americanheart.org/statistics/index.html
  5. Drummond ME, Jefferson TO. Guidelines for authors and peer reviewers of economic submissions to the BMJ. The BMJ Economic Evaluation Working Party. Br Med J. 1996;313:275–283[Free Full Text]
  6. Finkler S. Cost accounting for health care organizations: concepts and applications. Gaithersburg, MD: Aspen Publishers; 1994.
  7. Laupacis A, Feeny D, Detsky AS, Tugwell PX. How attractive does a new technology have to be to warrant adoption and utilization? Tentative guidelines for using clinical and economic evaluations. Can Med Assoc J. 1992;146:473–481[Abstract]
  8. Weinstein MC, Stason WB. Cost-effectiveness of coronary artery bypass surgery. Circulation. 1982;66:III56–111566
  9. Mark DB. Economic analysis methods and endpoints. Califf RM, Mark DB, Wagner GS. Acute Coronary Care. 2nd edn. St. Louis: Mosby; 1995. p. 167–182
  10. Goldman L, Garber AM, Grover SA, Hlatky MA. J Am Coll Cardiol. 10th edn. 1996. p. 1020–1030
  11. Shaw LJ, Eisenstein EL, Hachamovitch R, Kesler KL, Heller GV, Miller DD. A primer of biostatistic and economic methods for diagnostic and prognostic modeling in nuclear cardiology: Part II. J Nucl Cardiol. 1997;4:52–60[CrossRef][Web of Science][Medline]
  12. Gibbons R, Chatterjee K, Daley J, et al. ACC/AHA/ACPASIM guidelines for the management of patients with chronic stable angina. J Am Coll Cardiol. 1999;33:2092–2097[Free Full Text]
  13. Shaw LJ, Hachamovitch R, Heller GV, et al. Noninvasive strategies for the estimation of cardiac risk in stable chest pain patients. Am J Cardiol. 2000;86:1–7[Web of Science][Medline]
  14. Hachamovitch R, Berman DS, Shaw LJ, et al. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for the prediction of cardiac death. Circulation. 1998;97:535–543[Abstract/Free Full Text]
  15. Iskander S, Iskandrian AE. Risk assessment using single photon emission computed tomography technetium-99m sestamibi imaging. J Am Coll Cardiol. 1998;32:57–62[Abstract/Free Full Text]
  16. Berman DS, Shaw LL, Germano G. Nuclear Cardiology. Fuster V, Alexander RW, O'Rourke RA. Hurst's The Heart. 10th edn. New York: McGraw-Hill; 2001. p. 525–565
  17. Kymes SM, Bruns DE, Shaw LJ, Gillespie KN, Fletcher JW. Anatomy of a meta-analysis: a critical review of exercise echocardiography or exercise SPECT imaging: a metaanalysis of diagnostic test performance. J Nucl Cardiol. 2000;7:599–615[CrossRef][Web of Science][Medline]
  18. Underwood SR, Godman B, Salyani S, Ogle JR, Ell PJ. Economics of myocardial perfusion imaging in Europe — The EMPIRE study. Eur Heart J. 1999;20:57–166
  19. Shaw L, Hachamovitch R, Berman D, et al. The economic consequences of available diagnostic and prognostic strategies for the evaluation of stable angina patients: an observational assessment of the value of precatheterization ischemia. J Am Coll Cardiol. 1999;33:661–669[Abstract/Free Full Text]
  20. Braunwald E, Jones RH, Mark DB, et al. Diagnosing and managing unstable angina. Agency for Health Care Policy and Research. Circulation. 1994;90:613–622[Abstract/Free Full Text]
  21. Shaw LL, Heller GV, Travin MI, et al. Cost analysis of diagnostic testing for coronary artery disease in women with stable chest pain. J Nucl Cardiol. 10th edn. : Economics of Noninvasive Diagnosis (END) Study Group; 1999. p. 559–569
  22. LaRosa J, He J, Vupputuri S. Effect of statins on risk of coronary disease: a meta-analysis of randomized controlled trials. J Am Med Assoc. 1999;282:2340–2346[Abstract/Free Full Text]
  23. Pitt B, Waters D, Brown WV, et al. Aggressive lipid-lowering therapy compared with angioplasty in stable coronary artery disease. N Engl J Med. 1999;341:1854–1855

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?



This Article
Right arrow Abstract Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Disclaimer
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Shaw, L.J.
Right arrow Articles by Miller, D.D.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Shaw, L.J.
Right arrow Articles by Miller, D.D.
Social Bookmarking
 Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?