Preface
A growing consensus suggests that abdominal obesity—reflected by waist circumference—appears to be a better predictor of the risk of coronary artery disease, diabetes, and metabolic syndrome, than body mass index (BMI). In this supplement, a panel of experts come together to provide a review of the current state of knowledge on abdominal obesity and its association to adverse cardiovascular outcomes. In this issue, the pathophysiological links between intra-abdominal adiposity and elevated cardiometabolic risk are reviewed, suggesting a role of adipokines in the promotion of insulin resistance, diabetes, and the cluster of risk factors associated with the metabolic syndrome. Also, the implications of increased FFA production in the setting of abdominal obesity and insulin resistance are discussed. Last, but not least, the rationale and design of the IDEA (International Day for the Evaluation of Abdominal Obesity) survey are presented; the study will provide a global map of the prevalence of abdominal obesity and associated comorbidities in primary care practice.
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