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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2007. For permissions please email: journals.permissions@oxfordjournals.org

Optimizing the clinical use of implantable defibrillators in patients with Brugada syndrome

Andrea Sarkozy1,*, Pedro Brugada1, Lluis Mont2 and Josep Brugada2

1 Heart Rhythm Management Institute, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090-B Brussels, Belgium
2 Cardiology Department, Thorax Institute, University of Barcelona, Barcelona, Spain

* Corresponding author. Tel: +32 2477 6010; fax: +32 2477 6840. E-mail address: andreasarkozy{at}yahoo.ca

Our review highlights the difficulties we face when treating patients with Brugada syndrome (BS) by an implantable cardioverter defibrillator (ICD). Higher defibrillation thresholds, high inappropriate shock rates because of sinus tachycardia and supraventricular tachycardias, T wave oversensing, and high lead failure rates should be expected. Psychosocial adjustment problems also occur frequently in this patient population. These high complications rates are because of specific characteristics of the BS patient population, consisting of young, active patients with a primary electrical disease. The management strategies include prevention and early recognition of the expected complications. Additionally, individualized careful programming of the ICD is essential to ensure maximal safety and minimal complication rates in patients with BS.

Key Words: Brugada syndrome • Implantable cardioverter defibrillator • Ventricular tachyarrhythmias


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