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© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Role of cardiac biomarkers in assessment of RV function and prognosis in chronic pulmonary hypertension

Anna Fijalkowska* and Adam Torbicki

Department of Chest Medicine, Institute of Tuberculosis and Lung Diseases, Ul Plocka 26, 01-138 Warszawa, Poland

* Corresponding author. Tel: +48 22 4312114; fax: +48 22 4312414. E-mail address: a.fijalkowska{at}igichp.edu.pl

Humoral biomarkers emerged within the last decade as an attractive non-invasive tool for assessment and monitoring of right ventricular (RV) dysfunction in patients with pulmonary hypertension (PH). Combined with clinical assessment, they offer the possibility to reduce the frequency of traditional, time-consuming, complex, and costly tests. Echocardiography, right heart catheterization (RHC), or cardiac magnetic resonance (CMR) could then be reserved for detailed initial evaluation and for resolving more complex emerging clinical problems. Biomarkers would be particularly useful for outpatient monitoring and daily clinical practice. Our paper reviews the evidence collected so far in this dynamically developing area of cardiovascular medicine.

Key Words: Biomarkers • Pulmonary hypertension • Chronic heart failure • Right ventricular function • Prognosis


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