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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Early invasive strategy in elderly patients with non-ST-elevation acute coronary syndromes

Francesco Liistro*, Kenneth Ducci, Giovanni Falsini and Leonardo Bolognese

Cardiovascular Department, San Donato Hospital, Arezzo, Italy

* Corresponding author. Tel: +39 575254070; fax: +39 575254073. E-mail address: francescoliistro{at}hotmail.com

The clinical impact of an early invasive strategy (EIS) on elderly patients with acute coronary syndromes (ACSs) has yet to be completely defined because of the poor enrolment of elderly patients in randomized trials in this setting. The reluctance to treat elderly ACS patients is mainly due to the higher risk profile of these patients when percutaneous or surgical revascularization is planned. However, recent clinical data from different centres strongly support the use of an EIS in the elderly, showing a significantly larger absolute reduction in 30-day major adverse clinical events in elderly patients than that in younger patients, and prompt the need for dedicated randomized trials.

Key Words: ACS • Early invasive strategy • Elderly


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