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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org

Defining the prevalence of low HDL-C in a European cohort of dyslipidaemic patients

Eric Bruckert1,*, Raymond Pamphile2, Fran McCoy3 and Philippe André4

1Service d'Endocrinologie Métabolique, Groupe Hospitalier Pitié-Salpêtrière, 47, Boulevard de l'Hôpital, 75651 Paris Cedex 13, France
2Merck KGaA, Darmstadt, Germany
3IMS Health, London, UK
4Inserm U258, Villejuif, France

* Corresponding author. Tel: +331 42 17 78 49; fax: +331 42 17 78 65. E-mail address: eric.bruckert{at}psl.ap-hop-paris.fr

Low HDL-cholesterol is increasingly recognized as an independent risk factor for adverse cardiovascular outcomes, irrespective of levels of LDL-cholesterol. Although sporadic reports suggest that the prevalence of low HDL-cholesterol is substantial, we lack detailed data on the true prevalence of this condition among patients receiving treatment for dyslipidaemia. The Pan-European survey on HDL-cholesterol has collected data on levels of HDL-cholesterol, together with other lipid parameters and cardiovascular risk factors, from more than 9000 dyslipidaemic patients by 1350 specialist physicians in 11 European countries. A preliminary analysis of a subset of the participants in the survey suggests a population at markedly elevated cardiovascular risk. The detailed information from this survey, currently under analysis, will define the magnitude of the contribution of low HDL-cholesterol to dyslipidaemia in Europe and will focus on the need to include strategies for correcting low HDL-cholesterol within multiple risk factor intervention programmes.

Key Words: HDL-cholesterol • Prevalence • Atherosclerosis • Cardiovascular risk • Dyslipidaemia


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 Eur Heart J SupplHome page
E. Bruckert
Epidemiology of low HDL-cholesterol: results of studies and surveys
Eur. Heart J. Suppl., October 1, 2006; 8(suppl_F): F17 - F22.
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