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The European Society of Cardiology

Acute ischaemia as a trigger of sudden cardiac death

Kristian Thygesena,* and Barry F Uretskyb

a Department of Medicine and Cardiology, Aarhus Amtssygehus/University Hospital, Aarhus, Denmark
b University of Texas Medical Branch, Galveston, USA

Received 3 May 2004; accepted 24 May 2004.

* Kristian Thygesen, Department of Medicine and Cardiology, Aarhus University Hospital, Tage Hansens Gade 2, Aarhus C 8000, Denmark. Tel.: +45-8949-7614; fax: +45-8949-7619
kristian.thygesen{at}aas.auh.dk

Abstract

Sudden cardiac death remains a major mode of exitus in the general population but its mechanisms are incompletely clarified. Several triggers of sudden death have been described. Acute myocardial ischaemia from sudden worsening of coronary artery disease may be one of the most important. This review discusses current concepts regarding ischaemia as the trigger of sudden cardiac death.

Key Words: Sudden cardiac death • Coronary artery disease • Ischaemia • Heart failure


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