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Understanding the pathophysiology of the arterial wall: which method should we choose? Magnetic resonance imaging

V. Fuster*, R. Corti, Z.A. Fayad and J.J. Badimon

Mount Sinai Medical Center New York, U.S.A

* Correspondence: Professor Valentin Foster, Mount Sinai Medical Center, 1 Gustave Levy Place, Box 1030, New York, NY 10029, U.S.A.

Abstract

It has become increasingly recognized that it is the composition of plaque rather than the degree of stenosis that determines risk for plaque disruption, and therefore patient outcome. Magnetic resonance imaging (MRI) is the most promising method for imaging plaque non-invasively and determining different plaque components. It allows discrimination of lipid core, fibrosis, calcification and thrombus deposits. It can be used to study the progression of and the effects of treatment for cardiovascular disease (e.g. statin therapy) over time. MRI can also be used to assess accurately the activity of thrombi and determine when they become inactive. MRI technology is evolving rapidly and will open up new areas for diagnosis, treatment and prevention of atherosclerosis.

Key Words: Atherosclerosis • magnetic resonance imaging • plaque composition


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