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Evaluation of myocardial viability after myocardial infarction

R. Krishnamani and R. Senior*

Northwick Park Hospital, Harrow, Middlesex, U.K.

* Correspondence: Dr Roxy Senior MD, DM, FRCP(Lond), Consultant Cardiologist and Director of Echocardiography, Northwick Park Hospital, Watford Road, Harrow, Middlesex, HA1 3UJ, U.K.

Abstract

Early after acute myocardial infarction in patients who are stable, it is important to assess myocardial viability for both prognostic and therapeutic reasons. Myocardial contrast echocardiography is a technique that utilizes intra-vascular injection of microbubbles. These microbubbles traverse the myocardial vasculature, producing opacification during echocardiography. The microbubbles remain entirely within the intra-vascular space, and their presence within any myocardial region denotes the status of microvascular perfusion within that region. It has recently been shown that microvascular perfusion parallels myocardial viability. Myocardial contrast echocardiography has the potential to evolve into a reliable and simple bedside technique for the assessment of viable myocardium after acute myocardial infarction.

Key Words: Contrast echocardiography • myocardial viability • real-time perfusion imaging


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