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Prognostic value of myocardial perfusion imaging in patients with known or suspected coronary artery disease

K.C. Allman* and L.E.J. Thomson

Nuclear Cardiology Laboratory, Concord Hospital, Sydney, Australia

* Correspondence: Kevin C. Allman, Director of Nuclear Cardiology, Concord Hospital, Concord NSW 2139, Australia.

Abstract

Myocardial perfusion imaging (MPI) provides important prognostic information in patients with suspected or known coronary artery disease (CAD). There is well-documented evidence that patients with a normal or near-normal MPI study have a low cardiac event rate in the subsequent 1–2 years, whereas an abnormal MPI scan is indicative of increased risk (up to ten-fold) of such an event. Moreover, recent data indicate that MPI provides twice as much prognostic information compared with clinical and stress variables in these settings. Thus, MPI can be used as a ‘gateway’ to appropriate referral for invasive evaluation, enabling management to be targeted to high-risk patient groups to improve outcome.

Key Words: Myocardial perfusion imaging • coronary artery disease • prognosis


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